Virtual Conference
Neuroscience conference 2022

Wati Evilia

Udayana University, Indonesia

Title: Immune system and its relation to depression


It has been shown that the immune system and mental status are interrelated. Psychoneuroimmunology is a field that studies these two relationships, one of the most studied is the relationship between the immune system and depression. Psychological stress can substantially increase inflammatory activity and increase risk for various health problems. Social environmental conditions trigger biological responses that can lead to an increase in the proinflammatory phenotype, which then plays a role in the emergence and recurrence of depression and is associated with several somatic conditions. The immune system and depression have a bidirectional link that influences each other. Exposure to chronic stressful situations can cause a maladaptive response by the immune system, which will be involved in the pathophysiology of depression. There have been many studies in the field of psychoneuroimmunology that have focused on depression in its diagnosis and management. Further research is needed on an integrated system in the management of patients with depression associated with immune system function.


Wati Evilia is a certified general physician from Tarumanagara University, Jakarta. She is currently a senior resident at the Psychiatric Department of Udayana University, Bali. She also plays a vital role in giving psychiatry treatment in Sanglah Hospital, Denpasar during her residency, and also she teaches medical student in psychiatric rotation.  In addition, she had involved in numerous psychiatry symposiums and workshops. During her residency, Lia also developed a special interest in psychoneuroimmunology. Her motivation in regarding field has allowed her to conduct in vivo research studying probiotics as adjuvant therapy of depression in animal models in 2022.