Virtual Conference
Neuroscience conference 2023

Alem Amani

,, France

Title: Cognitive remediation in dementia: the earlier the better?


Introduction: Impairments in neuro cognition are considered core features of dementia since they affect patients' occupational functioning and compromise the quality of life. Drug treatments at present provide symptomatic relief. Psychosocial and other supportive therapies are needed. especially in the first phases of the disease, as early interventions may favor better outcomes. 

Objective: In this review, we aimed to describe studies that investigated the effect of Cognitive remediation on improving the neurocognitive in adults with MCI or early-stage dementia.

Methods: The literature review carried out focused on studies dating from 2010 to 2023. The databases were searched: ScienceDirect, PsycNET, PsycINFO, Pubmed The keywords used were MCI dementia. cognitive remediation review. Cognition A narrative synthesis of the findings was reported on the outcomes of the included studies. 

Results: A few studies tested the neural effects of CR in the early phase of the disease. 

A total of 329 participants were included from the 9 included studies. The mean age of participants ranged from 56 to 88 years, with 114 males and 215 females. 

Two studies One session per week three studies 3 sessions per week four studies having two session per week.

Five studies had up to 19 total hours of intervention two studies had between 20 and 39 total hours of intervention two studies had between 40 and 49 h of intervention  

Six studies implemented a group-based approach three studies adopting a one-to-one individual approach.

Discussion: This synthesis made it possible to highlight the main effects of Cognitive remediation in dementia: Little is known about the effectiveness of cognitive remediation on improving cognitive functions of daily living performance for individuals with mild cognitive impairment or early-stage dementia:

The meta-analysis included five studies with a total of 115 participants assessing the immediate effect of cognitive remediation.
This approach should be individualized and tailored to the individual’s needs.
Shorter intervention sessions may be more favorable. Intervention periods of 6 to 20 h seems more effective in enhancing memory, quality of life, and mood for older.

Conclusion: Cognitive remediation appears to be a promising approach in the treatment of cognitive deficits associated with the early phase of dementia. but there is insufficient statistical evidence to confirm any lasting effect. As such, further studies are needed to show the positive effect of this approach in this entity.